» Czw wrz 10, 2009 14:55
Re: Brzuchy białe dwa - Powtórka eksterminacji najmniejszych.
When taken orally enrofloxacin is well absorbed, and although the presence of food in the stomach may delay rate it does not seem to effect its absorption capability.
Enrofloxacin is well distributed throughout the body, and can be found in small concentrations in the cerebral spinal fluid. About 30-40% of the drug is metabolized to the human approved drug, ciprofloxacin.
Antacids and dairy products containing Magnesium, Calcium, and Aluminum may prevent absorption of enrofloxacin. It is suggested to separate dosing from any of these products by 2 hours.
Dr. Hutchinson has had some success with the long term, maintenance dosing of enrofloxacin 15 mg/kg BID PO (or in the presence of renal disease 8 mg/kg to 10 mg/kg BID) in conjunction with doxycycline 5 mg/kg BID PO, and based on his experience no discernable side effects have been noted.
The following drugs may be seen used simultaneously with enrofloxacin: aminoglycosides (e.g., amikacin or gentamicin), or aminopenicillins (e.g., amoxicillin or ampicillin), or third generation cephalosporins, or clindamycin, or doxycycline (for mycoplasma), or metronidazole.
Fluoroquinolones can induce a wide range of serious adverse psychiatric effects. These reactions may manifest as extreme anxiety, panic attacks, depression, anhedonia, cognitive dysfunction (or brain fog), depersonalization, paranoia, hallucinations, toxic psychosis, seizures, tremors, taste perversions, abnormal dreams, chronic insomnia, vertigo, delirium, suicidal thoughts and usually involves all five senses. For some people the symptoms resolve relatively soon after discontinuing the fluoroquinolone; for others in the case of a neurotoxic effect, symptomatology may persist for months or even years after discontinuation. Fluoroquinolones are associated with a significant number of serious psychiatric events.